Urine testsUrine tests: How long can THC metabolites be detected in urine?

Ellis and colleagues

Urine tests: The urinary excretion patterns of 86 users were examined after their last cannabis use by two common screening methods (…). We demonstrated that under very strictly supervised abstinence, chronic users can have positive results for in urine (…) for as many as 46 consecutive days from admission, and can take as many as 77 days to drop below the cut-off calibrator for 10 consecutive days. For all subjects, the mean excretion time was 27 days (…). Demographic, body type, and drug history variables proved to be only moderate predictors of excretion patterns.”

Ellis GM Jr Mann MA Judson BA Schramm NT Tashchian A. Excretion patterns of cannabinoid metabolites after last use in a group of chronic users. Clin Pharmacol Ther 1985;38(5):572-578.

Rolf Aderjahn

Excretion of THC and its metabolites in chronic users can be found in the range of 4-6 weeks. In the literature a 10 year long intensive cannabis use was reported to result in detection of use after 77 days with common tests. With single or occasional use excretion in urine is rarely short (some hours), usually it lasts for 3-5 days.

NOTIZIA COLLEGATA
Cannabis as treatment for sleep apnea

Aderjahn R. Toxikologischer Cannabisnachweis [Toxicological ]. In:  Berghaus G, Krüger HP, eds. Cannabis im Straßenverkehr [Cannabis in road traffic]. Stuttgart: , 1998.

Coleman en Baselt

OBJECTIVE: We have become aware of several that, when orally ingested, will purportedly not only eliminate “toxins” from a person’s system, but will also correct any urinary imbalances caused by excessive water consumption.

METHOD: Unblinded study of one volunteer subject, tested weekly x 4 for 24-hour urine elimination of test drug under conditions of control, control plus 1200 ml water, Quick Flush, and Eliminator.

RESULTS: Each of the protocols studied caused reductions of drug or metabolite concentrations as measured by gas chromatography-mass spectrometry in urine specimens (…), yet the radioimmunoassay demonstrated very little effect. Water alone was approximately as effective as the two commercial products in reducing the metabolite level. None of the treatment protocols employed in this study altered urinary , specific gravity, or creatinine outside the normally accepted physiological range.

CONCLUSIONS: Attempts to conceal drug abuse by water dilution are most likely to play a substantial role when concentrations are at or near the detection threshold for a particular assay such as the terminal stages of drug eliminations.

NOTIZIA COLLEGATA
The Life cycle of Cannabis: From seed to harvest

Coleman DE Baselt RC. Efficacy of two commercial products for altering urine results. J Toxicol Clin Toxicol (1997) 35(6):637-642.

 

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