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THC in blood: How long can THC and his metabolites be detected in blood?

With usual tests 0.5 nanograms per milliliter (ng/ml) of THC and 0.5 ng/ml of its THC-COOH can be detected in blood plasma. The time until falling short of this detection limit after consumption varies considerably, even if the same amount of THC was ingested.
After smoking a low dose cigarette (about 16 mg THC) the detection limit of 0.5 ng/ml THC in plasma was reached after 7.2 hours on average (range: 3-12 hours) and following a high dose cigarette (about 34 mg THC) a plasma of 0.5 ng/ml THC was reached within 12.5 hours (range: 6-27 hours). The metabolite THC-COOH was detectable for a considerably longer time, for 3,5 days (range: 2-7 days) after the low dose and for 6,3 days (range 3-7 days) after smoking the high dose cigarette.
The elimination half life for from plasma is longer than the elimination half life of the THC itsself. With regular use THC-COOH may be detectable in the plasma for several weeks.

NOTIZIA COLLEGATA
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Modified according to: and pharmacodynamics of . Clin Pharmacokin 2002, in press.

This post is also available in: itItaliano (Italian)

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